Psychiatry and
Behavioral Sciences

Combining Antidepressant Medication & Psychotherapy for Insomnia to Improve Depression Outcome

Principal Investigator: Rachel Manber, PhD

Insomnia in Depression

Difficulties falling and / or staying asleep are common in people who suffer from depression. Persistent insomnia can hinder response to treatment. Individuals whose insomnia does not resolve with standard antidepressant therapy are at increased risk for recurrence of their depression.

With the aim of improving the overall treatment of depression, our study will evaluate a treatment strategy that simultaneously treats sleep difficulties and depression. The study will evaluate whether or not this strategy will enhance clinical outcome and lead to longer lasting benefits.

What the study entails

Eligible participants in the study receive treatment with

To determine eligibility participants undergo some or all of the following diagnostics procedures:

For more information, contact 650-724-9774.

Where the study is conducted

This study is conducted at the Stanford Treatment Research Center (STRC), Stanford School of Medicine Department of Psychiatry and Behavioral Sciences.


The study is federally funded by the National Institutes of Mental Health (NIMH).

Recruiting through 2006

Some symptoms of depression

Relevant links with information about



Other depression research studies at Stanford:


Stanford Medicine Resources:

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